Focus on diagnostics
We process the data

Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.

One turnkey solution for all clinical NGS applications

Solution

The varvis® genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.

varvis genomics platform - Bioinformatics pipeline

Bioinformatics

Automated. Validated. Fast.

varfeed® automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs all bioinformatics, including alignment and clinically validated CNV/SNV/Indel variant calling. All results are handed over to varvis® automatically. Pipeline validation is provided as a service – updates are included.

varvis genomics software

varvis® genomics software

Made for use in clinical diagnostics

varvis® is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, varvis® is your own comprehensive variant database. It supports the clinical decision-making process and is a registered CE-IVD device according to directive 98/79/EC.

varvis genomics platform - Annotation

Annotation

Always up to date

allexes® provides the data for variant annotation to varvis®. allexes® does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users compliant with HIPAA and EU regulations.

Key benefits

 
Automated QC

Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.

 
Push the button

Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.

 
80% savings

Our clinically validated CNV analysis provides significant time and cost savings compared to ligation based CNV detection methods.

  
Overnight express

No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight. Guaranteed.

Use cases

varvis genomics platform use case - NGS panels

NGS panels

Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.

varvis genomics platform use case - whole exome sequencing

Whole exome
sequencing

Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.

varvis genomics platform use case - cancer diagnostics

Liquid biopsy

Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.

SARS-CoV-2
surveillance

The varvis® SARS-CoV-2 service minimizes the need for manual interaction and produces reports suitable for national agencies.

See for yourself how varvis® can accelerate your laboratory workflows and increase your diagnostic yield.

Let's schedule a demo!

Testimonials

Read more

varvis® blog - Watch now: Sharpening our tools for the diagnosis of mosaic disorders

Watch now: Sharpening our tools for the diagnosis of mosaic disorders

by Nadine Näser, September 9, 2021

In this session, our speakers highlight the specific challenges that physicians encounter while handling mosaic diseases and explain in detail how a suitable assay was established and validated.

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varvis® blog - Can you determine the specificity of an NGS assay?

Can you determine the specificity of an NGS assay?

by Dr. Ben Liesfeld, September 7, 2021

We have seen this many times: scientists calculate the sensitivity and specificity of their NGS assay. These are the standard performance metrics of a clinical test based on NGS — or are they?

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How to perform carrier screening using the varvis® software

by Yvonne Kasmann, June 4, 2021

Carrier screening enables the analysis of two unaffected individuals who might be carriers of disease-causing variants. Here we will show how these variants can quickly be identified in varvis® even for expanded carrier screening tests.

Read more

Find more interesting articles in our blog

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