Revolutionizing clinical diagnostics with long-read sequencing using the varvis® software
An IVDR Class C certified platform
for secondary & tertiary analysis of long-read data.
How it works
From raw data to actionable insights —
the varvis® platform facilitates and simplifies the analysis of complex long-read sequencing data.
Unlock insights from complex genomes
Enabling the detection of complex genetic variation and variant phasing to deliver actionable insights from long-read data — driving accurate and comprehensive clinical diagnostics.
Key analytical capabilities
Repeat expansion analysis
Detect pathogenic short repeat expansions (STRs) linked to neurological and rare diseases. Our platform flags variants as pathogenic based on repeat count thresholds. No more manual counting!
All variant details in one view
Access all essential information – from STR counts and variant annotation to phenotype association in a single, structured interface to accelerate interpretation and to support confident clinical decision-making.
Accurate structural variant detection
Identify complex structural variants across the genome — complete with phasing and high-resolution breakpoint accuracy.
Why choose the varvis® software?
The varvis® software is a CE-IVD certified software solution for both short- and long-read sequencing analysis. Designed specifically for clinical diagnostics, the varvis® software automates IT, data processing, and quality control, allowing you to focus on delivering accurate and timely insights for patient care. With proven analytical performance, the platform ensures high-confidence results for genomic data, from SNVs to tandem repeats and complex structural variants (SVs). Whether you are working with whole genomes or targeting difficult regions, the varvis® software provides an easy and effective solution to aid your clinical decisions, making it your reliable tool in precision medicine.
Short and long-read
data analysis
Analyze both data types side by side in one unified platform - no need for multiple tools.
Trust your results
From SNV and CNV analysis, to Short Tandem Repeat (STR) and complex re-arrangements, detect and classify variants with proven analytical performance.
All-In-One
Valuable reference data for STRs and SVs to enhance and accelerate data interpretation (gnomAD-SV, DECIPHER, DGV and STRchive).
One-for-All sequencing
From challenging dark regions to whole genome, support any use case - at scale.
Truly Hands-Free operation
Automated IT, data processing and quality control - no manual setup needed.
Certified
CE-IVD certified to meet regulatory standards and support patient diagnostics.
Long read sequencing is ready for clinical diagnostics!
Unlock the full potential of long-read sequencing. Elevate your analysis and uncover deeper insights from your genetic data with the varvis® software.
Read more
Update to gnomAD v4.1: Key features
by Dr. Roberta Trunzo, August 27, 2024
The varvis® software now includes the latest version of the Genome Aggregation Database (gnomAD), providing updated annotations for whole exome and whole genome data. This article describes the enhancements and implications of the update to the new version 4.1, particularly for clinical diagnostics.
The varvis® Software: The first genomics end-to-end software certified as IVDR Class C device
by Dr. Ben Liesfeld, May 31, 2024
Genetic diagnostic laboratories now have access to the first complete genomics software solution which is certified as a Class C device under IVDR. This will significantly reduce the effort required for legally compliant documentation of in-house tests.
The varvis® onboarding process
by Dr. Roberta Trunzo, April 16, 2024
Welcome to the varvis® software! We understand that, as a new customer, navigating through a new software platform can be overwhelming. That’s why we’ve created this comprehensive guide to get an overview of all the steps in the process. Our mission? To facilitate a smooth onboarding to our reliable and high-performance varvis® software and this step-by-step walk-through will ensure you make the most out of it.