Focus on diagnostics
We process the data

Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.

One turnkey solution for all clinical NGS applications

NGS panels

Whole exome sequencing

Cancer diagnostics


The varvis® genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.


Automated. Validated. Fast.

varfeed® automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs all bioinformatics, including alignment and clinically validated CNV/SNV/Indel variant calling. All results are handed over to varvis® automatically. Pipeline validation is provided as a service – updates are included.

varvis® genomics software

Made for use in clinical diagnostics

varvis® is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, varvis® is your own comprehensive variant database. It supports the clinical decision-making process and is a registered CE-IVD device according to directive 98/79/EC.


Always up to date

allexes™ provides the data for variant annotation to varvis®. allexes™ does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users compliant with HIPAA and EU regulations.

Key benefits

Automated QC

Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.

Push the button

Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.

80% savings

Our clinically validated CNV analysis provides significant time and cost savings compared to ligation based CNV detection methods.

Overnight express

No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight. Guaranteed.

Use cases

NGS panels

Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.

Whole exome sequencing

Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.

Cancer diagnostics

Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.

See for yourself how varvis® can accelerate your laboratory workflows and increase your diagnostic yield.

Let's schedule a demo!


Read more

Watch now: Whole exome analysis in routine diagnostics

by Nadine Naeser, June 26, 2020

Using real case examples from high-throughput diagnostics, our speakers show you how they use varvis® to streamline and accelerate WES analysis in their everyday clinical practice.

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The human reference genome hg38 in clinical diagnostics

by Ben Liesfeld, June 10, 2020

hg38 is the old new standard for genomics. It has been more than 6 years since the official release of hg38 in 2013. Even though it provides many improvements over the “old” hg19 reference, it has not been adopted widely in clinical diagnostics. Here are a few things to consider in a cinical lab when migrating to hg38.

Read more

Automated ClinVar alerts

by Ben Liesfeld, May 13, 2020

Our knowledge of the significance of genomic variants is changing at a fast pace. The increasing number of submissions to the public database ClinVar is illustrating our progress.

Read more

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