Focus on diagnostics
We process the data
Cloud-based genetic diagnostics to accelerate laboratory workflows and enhance patient care.
One turnkey solution for all clinical NGS applications
NGS panels
Whole exome sequencing
Cancer diagnostics
Solution
The varvis® genomics platform is a complete solution for clinical diagnostics, supporting NGS raw data processing, genomics data management, and variant interpretation. Automated CNV and SNV analysis are clinically validated and completely integrated into the NGS workflow.
Bioinformatics
Automated. Validated. Fast.
varfeed® automates the processing of raw next-generation sequencing data from bcl, fastq or bam files. It performs all bioinformatics, including alignment and clinically validated CNV/SNV/Indel variant calling. All results are handed over to varvis® automatically. Pipeline validation is provided as a service – updates are included.
varvis® genomics software
Made for use in clinical diagnostics
varvis® is a clinical decision support system (CDS) and allows you to review, filter, and classify genetic variants. In addition, varvis® is your own comprehensive variant database. It supports the clinical decision-making process and is a registered CE-IVD device according to directive 98/79/EC.
Annotation
Always up to date
allexes® provides the data for variant annotation to varvis®. allexes® does not only deliver the most recent versions of public databases, but also provides access to aggregated genomic reference data from all our users compliant with HIPAA and EU regulations.
Key benefits
Automated QC
Important quality metrics are monitored automatically for every single NGS sample, but also across batches over time. Don't waste a moment on manual QC.
Push the button
Convenient filtering options such as inheritance filters and virtual panels allow you to filter from thousands of detected SNVs and CNVs. Within seconds.
80% savings
Our clinically validated CNV analysis provides significant time and cost savings compared to ligation based CNV detection methods.
Overnight express
No matter how many samples or how many sequencing runs you have: our fully automated process delivers results overnight. Guaranteed.
Use cases
NGS panels
Identify rare and causative SNV and CNV in a single validated process and replace conventional PCR-based methods.
Whole exome sequencing
Do you need more than 15 minutes to interpret a whole exome? Accelerate WES interpretation by combining phenotype, family and inheritance information.
Cancer diagnostics
Detect somatic variants with validated high sensitivity using state-of-the-art molecular barcoding technologies.
See for yourself how varvis® can accelerate your laboratory workflows and increase your diagnostic yield.
Testimonials
University of Magdeburg
University of Leipzig
Synlab Zentrum für Humangenetik Mannheim
University of Göttingen
Read more
Limbus, University of Rostock win grant to apply AI to variant interpretation
by Ben Liesfeld, November 17, 2020
The Modeling and Simulation Group at the University of Rostock joins forces with Limbus Medical Technologies GmbH in the 1.5 mEUR research project IDEA-PRIO to enhance the interpretation of genetic variants using artificial intelligence (AI) methods.
Watch now: Diagnosing intellectual disability using exome analysis — you can do it!
by Yvonne Kasmann, October 18, 2020
During our corporate satellite at the Jornada AEGH 2020 we talked with our clinical expert, Prof. Rami Abou Jamra (University of Leipzig Medical Center) about why adequate and efficient exome analysis is the method of choice when diagnosing intellectual disabilities.
RefSeq Select — a standardized algorithm to select your preferred RefSeq transcript
by Ben Liesfeld, October 2, 2020
Which transcript should I use to report a genomic variant? This is a frequent question from clinical geneticists now that Whole Exome Sequencing, which targets all known genes, has become widely available in clinical diagnostics.