Navigate the NGS
universe with confidence
varvis® is your cloud-based and highly automated turn-key solution for all clinical NGS applications - from NGS panels and whole exomes to whole genomes including cancer diagnostics and carrier screening.
One software solution for all NGS Use Cases
Each NGS application has its own challenges and requirements, tiny gears that have to work together perfectly.
varvis® is your one turnkey solution that integrates into your diagnostic workflow seamlessly including NGS raw data processing, genomics data management, and variant interpretation. The software offers you an intuitive navigation user interface that provides you with convenient filtering options and enables you to easily identify, classify, and report relevant genetic variants. The automated and clinically validated CNV and SNV analyses save you time and costs and with our expert support, onboarding, and training you are all set to go.
See for yourself how varvis® can accelerate your laboratory workflows
and increase your diagnostic yield.
Read more
An MDCG Guideline for Laboratory Developed Tests Under IVDR
by Dr. Ben Liesfeld, January 25, 2023
There have been a lot of discussions about what IVDR Art 5(5) means for genetic diagnostic labs. In January 2023, the Medical Device Coordination Group issued a guideline that clarifies important items. This is our summary.
Known issues with genome build hg38
by Dr. Ben Liesfeld, August 19, 2022
Back in 2020 we were advertising hg38 as the better reference genome and highlighted potential challenges when transitioning from hg19 to hg38. More recently, the work of the T2T consortium revealed previously unknown shortcomings of hg38 which we will discuss here.
The varvis® advantage in CNV analysis
by Pragathi Prakash, April 8, 2022
When analysing large NGS assays usually dozens to hundreds copy number variants (CNVs) are expected. With integration of DGV, DECIPHER and the proprietary database allexes®, the varvis® software makes it easy to focus on the most significant variants.